CHRONOBIOLOGY METHOD

Skincare in sync with your
skin's natural rhythm

Our skin is governed by time. Every cell follows innate 24-hour rhythms of protection and renewal. When these rhythms stay intact, the skin preserves its vitality, resilience, and youthful appearance. But when disrupted, cellular health declines and aging accelerates.

Discover GEZEITEN’s groundbreaking chrono-biological method - a new frontier in skin longevity. Through intelligent rituals, programmed ingredient release, and rhythm-correcting actives, we restore harmony at the cellular level, strengthening resilience and redefining how skin ages.

methodology

At GEZEITEN, we have collaborated with Prof. Dr. Gregor Eichele from the Max Planck Institute to pioneer a chrono-biological skincare method. Our chrono-adaptive routines harness the body’s innate intelligence – its natural rhythm of protection and renewal – and translate it into intuitive skincare. This enables the skin to perform at its best without overload from excessive products or conflicting ingredients.

Welcome to a new generation of skincare – adaptive, intelligent, and perfectly in sync with your skin’s rhythm.



Chrono-adaptive rituals

We design dedicated day and night rituals that sync with your skin’s natural rhythm, addressing its distinctive needs at every phase. Effortless in application, each product works in synergy to strengthen skin functionality and long-term health.
Programmed ingredient release

Our formulas feature intelligent release systems that deliver actives when the skin is most receptive. This maximizes efficacy while avoiding irritation.
Rhythm-correcting actives

Powered by marine biotechnology, our ingredients actively help reset disrupted skin rhythms. They restore balance, strengthen resilience, and support long-term skin health.

Chrono-Phase Day: The Skin's Daytime Rhythm

6 – 9 AM Wake & Protect

The skin's barrier strengthens and sebum production begins, yet the skin looks tired due to nocturnal water loss.

OUR FOCUS Strengthen the skin barrier, maintain hydration and prevent trans-epidermal water loss for a smoother, fresher complexion.
10 AM – 2 PM Defense Mode & Cell Protection

Sebum production peaks, the pH level is acidic and the antioxidant defence system is at its most active. The skin fights UV rays and pollution.

OUR FOCUS Protect against blue light and digital aging, prevent photoaging and hyperpigmentation, defend against environmental stressors and free radicals – while supporting cellular vitality and resilience to preserve long-term skin longevity.
3 – 6 PM Fatigue & Stress

Hydration levels drop and oxidative stress rises. The skin looks tired, dull and stressed.

OUR FOCUS Balance stress-induced skin ageing, slow collagen breakdown and loss of elasticity, and soothe inflammation to restore your glow, refine your pores, and improve your skin's uniformity.

 DISCOVER THE DAY ROUTINE

Chrono-Phase Night: The Skin's Night-Time Rhythm

7 – 10 PM Open Gateway

Circulation increases, the skin becomes warmer and more permeable, and the repair process begins.

OUR FOCUS Stabilising the microbiome, soothing the skin and preparing it to absorb actives.
11 PM – 4 AM Detox & Senescent Cell Clearance

The skin begins to eliminate senescent cells, which are dysfunctional cells that trigger inflammation and accelerate aging. This natural 'cellular disrepair management' process lies at the heart of longevity science, helping to maintain skin vitality over time.

OUR FOCUS Activation of the skin’s innate longevity mechanisms by activating cellular renewal and recycling processes (autophagy), enhancing natural detox pathways, and preventing night-time water loss through intensive hydration. This ensures the skin recovers overnight and preserves its long-term health and resilience.
2 – 4 AM Peak Repair & Renewal

Cell repair and growth peak, and DNA is corrected and collagen built.

OUR FOCUS Boosting collagen and elastin synthesis to restore firmness and elasticity and supply essential nutrients while the skin is most receptive.
4 – 5 AM Sensitivity & Reset

Skin is more sensitive, cortisol rises and the barrier rebuilds.

OUR FOCUS Intensive replenishment, including hydration, calming, repair of inflammation-induced micro-damage and strengthening of the barrier.

 DISCOVER THE NIGHT ROUTINE

Out of rhythm, skin ages faster. Our chrono-adaptive formulas restore harmony – strengthening, renewing, and keeping skin visibly resilient.

SCIENTIFIC TEAM

FOUNDER & HEAD OF INNOVATION

Michaela Hiltebrandt set out to redefine skincare by uniting nature and science with the body’s own intelligence. Guided by its innate rhythms of protection and renewal, she creates formulas that respect and enhance the skin’s natural processes. Identifying ingredients for purity, potency, bioavailability and proven...

LEADING CHRONOBIOLOGY SCIENTIST

Prof. Dr. Gregor Eichele, one of the world’s foremost chronobiology experts with more than 20 years of research at the Max Planck Institute, has pioneered the study of the body’s internal clocks and their influence on health and regeneration. His pioneering work is the scientific...

MARINE BIOTECHNOLOGY SCIENTISTS

Under the scientific direction of Prof. Dr. Pierre-Yves Morvan, Doctor of Cellular Biology, CODIF Technologie Naturelle in Brittany, France, is a pioneer in marine biotechnology with more than 20 years of expertise. With over 40 patented marine actives and more than 200 clinical studies, CODIF...

Testimonials

HEATHER KEMESKY ∙ MODEL

How does that little bottle of liquid stardust turn my skin to glass?

NIKKI DEROEST ∙ MAKE-UP ARTIST

The most incredible packaging l've EVER laid eyes on.

LERA ABOVA ∙ ACTRESS & MODEL

The cream that did wonders to my 30 year young skin after 3 days.

LEANNE ELLIOTT YOUNG

Obsessed! It's just heaven! I've had so many DM's about it. Soo chic.

VERONIKA HEILBRUNNER

Obsessed.

Testimonials

HEATHER KEMESKY ∙ MODEL

How does that little bottle of liquid stardust turn my skin to glass?

NIKKI DEROEST ∙ MAKE-UP ARTIST

The most incredible packaging l've EVER laid eyes on.

LERA ABOVA ∙ ACTRESS & MODEL

The cream that did wonders to my 30 year young skin after 3 days.

LEANNE ELLIOTT YOUNG

Obsessed! It's just heaven! I've had so many DM's about it. Soo chic.

VERONIKA HEILBRUNNER

Obsessed.